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Check out some of our latest original content that was created and distributed as part of our ongoing collaborations with IR firms and other companies.

Soligenix Inc. (NASDAQ: SNGX) HyBryte(TM) Paves Way for Breakthrough Treatment for Rare Skin Cancer

  • The global rare disease treatment market was estimated at $195.2 billion in 2024 and is anticipated to expand at a CAGR of 11.6% by 2030.
  • SNGX’s HyBryte(TM) has demonstrated positive results in a study testing its use for patients with early-stage CTCL.
  • HyBryte(TM) is a novel therapy based on photodynamic therapy, which combines light and a photosensitizer to target and destroy cancer cells.

The development of treatments for rare diseases remains one of the most pressing challenges in modern medicine. Despite significant advancements in healthcare, many rare diseases still have no approved treatments, and patients often face grim prospects. The market for treatments in this space is substantial, as rare diseases collectively affect millions of people worldwide. Among those working tirelessly to fill these gaps is Soligenix (NASDAQ: SNGX), a biopharmaceutical company that is leading the way with innovative therapies for rare and difficult-to-treat diseases, particularly early-stage cutaneous T-cell lymphoma, a rare form of cancer that affects the skin.

The global market for rare disease treatments is growing at an impressive rate. According to a report by Grand View Research, the global rare disease treatment market was estimated at $195.2 billion in 2024 and is anticipated to expand at a CAGR of 11.6% by 2030 (https://ibn.fm/ePKDT).

“The presence of a strong product pipeline and their expected launches are expected to drive market growth,” the report stated. “For instance, in October 2024, the FDA announced seven new clinical trial grants for advancement in research on rare disease treatments, which are often overlooked. These new projects include the treatment for cancer, Cushing’s syndrome, lymphatic malformations, inherited eye disease and blood disorders. Increased funding for such research projects fuels the launch of new drugs and treatments for diseases and further boosts the market growth.”

Historically, research into rare diseases has faced several challenges, including limited patient populations, the high cost of clinical trials and the complexity of the diseases themselves. However, there have been notable success stories in recent years that demonstrate the potential for breakthrough treatments in this area.

The success of these treatments highlights the enormous potential for progress in rare disease research. For many years, diseases such as cutaneous T-cell lymphoma (“CTCL”) were considered difficult to treat due to their rarity and the challenges of developing targeted therapies. CTCL is a rare type of cancer that originates in the skin and affects the T-cells, a type of white blood cell. It is difficult to diagnose and treat, especially in its early stages, and most treatments are aimed at managing symptoms rather than providing a definitive cure. However, ongoing research and clinical trials are shedding light on potential therapies that may offer a more effective approach to treating CTCL and other rare diseases.

This is where Soligenix comes in. The company has been making significant strides in developing innovative therapies for rare and hard-to-treat diseases, including early-stage cutaneous T-cell lymphoma. Soligenix’s proprietary treatment, HyBryte(TM), is currently in clinical trials, and the latest results have shown promising efficacy in treating CTCL (https://ibn.fm/OB4Vd).

According to the most recent news from the company, HyBryte(TM) has demonstrated positive results in a study testing its use for patients with early-stage CTCL. “Following 18 weeks of treatment, 75% of patients achieved ‘Treatment Success,’ reinforcing HyBryte(TM) as a potentially safe and fast-acting therapy for this chronic and underserved cancer,” the company reported. The study results suggest that the treatment may be highly effective in reducing the symptoms of CTCL, providing much-needed hope for patients with this challenging condition.

HyBryte(TM) is a novel therapy based on photodynamic therapy (“PDT”), which combines light and a photosensitizer to target and destroy cancer cells. PDT has been used in the treatment of various cancers, but Soligenix has taken this approach a step further by developing a proprietary drug formulation that is specifically designed for the treatment of CTCL. The recent study results are encouraging, showing that HyBryte(TM) is not only effective but also well-tolerated by patients, with minimal side effects. This is particularly important for patients with rare diseases, as they often face significant challenges in tolerating conventional treatments.

The positive results from the HyBryte(TM) study are a significant step forward for Soligenix, positioning the company as a leader in the development of treatments for rare and difficult-to-treat diseases. Soligenix has demonstrated a clear commitment to addressing the unmet medical needs of patients with rare diseases, and the success of its ongoing research efforts could lead to the approval of a much-needed therapy for CTCL and other rare cancers. The company’s innovative approach, coupled with the growing market for rare-disease treatments, underscores the importance of continued investment in research and development in this critical area of healthcare.

For more information, visit www.Soligenix.com.

NOTE TO INVESTORS: The latest news and updates relating to SNGX are available in the company’s newsroom at https://ibn.fm/SNGX

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Soligenix Inc. SNGX | Leave a comment

MissionIRNewsBreaks – HeartBeam Inc. (NASDAQ: BEAT) to Report Q1 2025 Results and Provide Business Update on May 13

HeartBeam (NASDAQ: BEAT) will host a conference call on May 13 at 4:30 p.m. Eastern to discuss financial results for the first quarter ended March 31, 2025. CEO Robert Eno and CFO Timothy Cruickshank will lead the call, which will include updates on regulatory progress, commercial-readiness efforts, and upcoming milestones. A corresponding press release and presentation will be available on the company’s investor relations website.

To view the full press release, visit https://ibn.fm/MXmYz

About HeartBeam Inc.

HeartBeam is a medical technology company dedicated to transforming cardiac care by providing powerful cardiac insights wherever the patient is. The company is creating the first-ever cable-free 12-lead ECG capable of capturing the heart’s electrical signals from three dimensions. This platform technology is designed to be used in portable devices that can be used wherever the patient is to deliver actionable heart intelligence. Physicians will be able to identify cardiac health trends and acute conditions and direct patients to the appropriate care — all outside of a medical facility, thus redefining the future of cardiac health management. The company holds 13 U.S. and 4 international-issued patents related to technology enablement. For more information, visit www.HeartBeam.com .

NOTE TO INVESTORS: The latest news and updates relating to BEAT are available in the company’s newsroom at https://ibn.fm/BEAT

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Austin, Texas
www.MissionIR.com
512.354.7000 Office
[email protected]

MissionIR is powered by IBN

Posted in HeartBeam Inc. BEAT | Leave a comment

Calidi Biotherapeutics Inc. (NYSE American: CLDI) Committed to Advancing Cancer Care with Innovative RTNova Platform Research

  • Cancer statistics underscore the urgency of ongoing cancer research and the need for more effective cancer treatments.
  • Calidi Biotherapeutics has announced preclinical results for its RTNova platform, a breakthrough in the delivery of transient gene therapy payloads to targeted tumors.
  • The trials show an ability to deliver therapeutic payloads with precision while simultaneously attacking tumors.

Cancer remains one of the deadliest diseases worldwide. Globally, the World Health Organization reports that the number of deaths will surpass 9.7 million in 2024, with a projected 20 million new cancer cases diagnosed; WHO also noted that it anticipates the cancer burden increasing an estimated 77% by 2050 (https://ibn.fm/VfZlY). These numbers underscore the urgency of ongoing cancer research and the need for more effective cancer treatments.

This is where cutting-edge innovations, such as those pioneered by Calidi Biotherapeutics (NYSE American: CLDI), come into play. Calidi Biotherapeutics recently announced promising preclinical results for its RTNova platform, a breakthrough in the delivery of transient gene therapy payloads to targeted tumors (https://ibn.fm/bbPdB). This novel platform has demonstrated an impressive ability to successfully deliver therapeutic agents to tumor cells while minimizing damage to surrounding healthy tissues. By targeting tumors more effectively, this approach holds the potential to significantly improve treatment outcomes and reduce side effects.

Progress in cancer research has led to remarkable advancements that have improved survival rates and quality of life for many patients. From the development of targeted therapies and immunotherapies to advancements in precision medicine, these breakthroughs have reshaped the landscape of cancer treatment. Preclinical and clinical trials play a vital role in this progress by testing new drugs, therapies and treatment combinations, ensuring that only the most effective and safest options reach patients.

The journey from concept to clinical application is long and complex, with preclinical studies playing a critical role in determining the safety and efficacy of new therapies. These studies involve rigorous testing in laboratory settings, where researchers evaluate how well a treatment works on cancer cells and assess its safety before moving on to human clinical trials. Calidi’s success in preclinical models is a promising sign that its RTNova platform and tumor-specific virotherapy may achieve statistical efficacy in clinical evaluation, offering a glimpse of hope for future cancer patients.

Preclinical data provides crucial insights into how a therapy interacts with cancer cells, paving the way for carefully designed clinical trials. In the case of Calidi’s RTNova platform, the ability to deliver therapeutic payloads with precision while simultaneously attacking tumors represents a significant leap forward in cancer treatment strategies. This innovative approach could potentially revolutionize how gene therapy is applied to various cancer types, enhancing the immune response and improving treatment outcomes for patients.

As the global burden of cancer continues to rise, the need for groundbreaking therapies becomes even more urgent. Companies such as Calidi Biotherapeutics are leading the charge in developing transformative therapies that have the potential to change the course of cancer treatment. With the company’s ongoing research and deep commitment to scientific excellence, Calidi’s RTNova platform and tumor-specific virotherapy hold the promise of offering new hope to cancer patients, addressing the limitations of existing treatments, and potentially improving survival rates across multiple cancer types.

For more information, visit www.CalidiBio.com.

NOTE TO INVESTORS: The latest news and updates relating to CLDI are available in the company’s newsroom at https://ibn.fm/CLDI

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Calidi Biotherapeutics Inc. CLDI | Leave a comment

Nutriband Inc. (NASDAQ: NTRB) Leadership Team: Driving Innovation and Shaping the Future of Global Healthcare

  • Sheridan was recently named as a finalist for the 2025 EY Entrepreneur of the Year Awards
  • The CEO’s international perspective and expertise were further validated when he was featured in a recent BBC News article
  • Chairman Serguei Melnik also participated in a market interview where he spoke about Nutriband’s mission, achievements and plans for the future

Nutriband (NASDAQ: NTRB) is earning widespread recognition for the board’s leadership, expertise and innovation across a variety of platforms. Sheridan has recently been acknowledged in several high-profile ways that affirm his growing influence as a respected professional in the healthcare and business sectors. From being named a finalist for the prestigious EY Entrepreneur of the Year Awards to providing key insights in a BBC News feature on Irish companies operating internationally and sharing their strategic vision in a wide-ranging interview, NTRB’s voice is increasingly shaping discussions around entrepreneurship, innovation and the future of healthcare.

In a major milestone for his career, Sheridan was recently named as a finalist for the 2025 EY Entrepreneur of the Year Awards (https://ibn.fm/U1Tpb). He has been recognized in the International Category, which honors entrepreneurs whose companies have a significant footprint beyond their home countries.

The EY Entrepreneur of the Year program is considered one of the most prestigious accolades for business leaders worldwide, celebrating individuals who not only demonstrate exceptional business acumen but who also embody vision, leadership and innovation. Being shortlisted in this global category is a significant achievement, placing Sheridan among the elite group of entrepreneurs who are not just excelling in their home markets but are actively shaping industries on a global scale. This recognition serves as a testament to Sheridan’s ability to lead Nutriband into new markets and pioneer technologies that have international significance.

Sheridan’s international perspective and expertise were further validated when he was featured and quoted in a recent BBC News article discussing Irish businesses expanding into the U.S. market (https://ibn.fm/3yRSp). The article examined the shifting landscape for Irish companies as they seek growth opportunities in America, particularly in sectors such as pharmaceuticals, technology and manufacturing.

Sheridan, representing Nutriband as an Irish-founded company operating in the United States, offered valuable insights into the challenges and opportunities of such a transition. He noted that while the American market presents significant potential, success depends on a company’s ability to adapt and innovate within a highly competitive and regulated environment.

“The market is there for Irish companies that are innovative and prepared to scale globally, but you must understand the nuances of operating within the American regulatory and commercial environment,” said Sheridan. His comments, featured prominently among those of other seasoned entrepreneurs and policymakers, reflect Sheridan’s respected status in the international business community and underscore his firsthand understanding of what it takes to succeed on the global stage.

Adding further to NTRB’s growing public profile, Melnik participated in a detailed YouTube market interview where he spoke about Nutriband’s mission, achievements and plans for the future (https://ibn.fm/4bFtl). During the interview, Sheridan outlined the evolution of Nutriband from its early days to its current role as a pioneer in abuse-deterrent transdermal drug delivery technologies. He explained the scientific foundation behind AVERSA(TM), Nutriband’s flagship product designed to deter the abuse of opioid medications through innovative patch technology.

Melnik also emphasized the importance of pairing innovation with regulatory navigation, highlighting the significance of the FDA’s fast-track designation for AVERSA and the company’s commitment to bringing safer medications to the market. Throughout the interview, Serguei conveyed a blend of technical expertise and visionary thinking, showcasing not only a deep understanding of the healthcare challenges facing the world today but also a clear strategic roadmap for addressing them through Nutriband’s technologies.

NTRB demonstrates the qualities that are increasingly making this company a standout name in healthcare. The team’s ability to seamlessly bridge scientific innovation with global business strategy positions them uniquely among today’s new generation of CEOs. Whether driving Nutriband’s growth through regulatory milestones, navigating international expansion or sharing insights with a broader audience, Nutriband consistently exhibits the forward-thinking mindset and leadership required to build sustainable, impactful companies in today’s complex global environment.

As Nutriband continues to advance its mission to improve patient safety through innovative transdermal delivery systems, the board’s influence and leadership are key driving forces behind its success. Their recent recognition and contributions to important industry conversations are not only well-deserved but are also setting new standards for what healthcare entrepreneurship can achieve on a global scale.

For more information, visit the company’s website at www.Nutriband.com.

NOTE TO INVESTORS: The latest news and updates relating to NTRB are available in the company’s newsroom at https://ibn.fm/NTRB

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Nutriband Inc. NTRB | Leave a comment

MissionIRNewsBreaks – Platinum Group Metals Ltd. (NYSE American: PLG) (TSX: PTM) CEO Spotlights Waterberg Project on MiningNewsWire Podcast

Platinum Group Metals (NYSE American: PLG) (TSX: PTM) is featured in the latest episode of The MiningNewsWire Podcast, where Co-Founder, Director, President and CEO Frank R. Hallam discusses the company’s flagship Waterberg Project in South Africa. Hallam highlights how the deposit—discovered in 2011—stands apart with its shallow depth and exceptional thickness, enabling safer, more cost-efficient, and highly mechanized mining. Unlike traditional South African platinum operations that rely on deep, labor-intensive shafts, Waterberg allows for decline access and heavy machinery. Hallam also shares insights on Lion Battery Technologies, the company’s joint venture exploring platinum and palladium applications in lithium batteries, as part of Platinum Group Metals’ innovation strategy.

To view the full press release, visit https://ibn.fm/Q1HgP

About Platinum Group Metals Ltd.

Platinum Group Metals is the operator of the Waterberg Project, a bulk underground palladium and platinum deposit located in South Africa. The Waterberg Project was discovered by Platinum Group and is being jointly developed with Implats, Mnombo and HJM. For more information about the company, visit www.PlatinumGroupMetals.net.

NOTE TO INVESTORS: The latest news and updates relating to PLG are available in the company’s newsroom at https://ibn.fm/PLG

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Austin, Texas
www.MissionIR.com
512.354.7000 Office
[email protected]

MissionIR is powered by IBN

Posted in Platinum Group Metals Ltd. PLG | Leave a comment

MissionIRNewsBreaks – Eloro Resources Ltd. (TSX.V: ELO) (OTCQX: ELRRF) (FSE: P2QM) Launches Next Phase of Drilling at Iska Iska Silver-Tin Project

Eloro Resources (TSX: ELO) (OTCQX: ELRRF) (FSE: P2QM), advancing its Iska Iska silver-tin polymetallic project in southwestern Bolivia, will soon begin a 4,300-meter, eight-hole diamond drilling program targeting the Santa Barbara starter pit area. The campaign is designed to upgrade and expand high-grade tin and silver mineralization, with holes spaced at 50 meters to confirm continuity. CEO Tom Larsen said prior drilling extended mineralization and revealed new targets, contributing to a significantly expanded footprint. The upcoming 2025 phase 1 campaign will further assess the zone’s resource potential to support an updated PEA, with ongoing metallurgical studies showing promising results.

To view the full press release, visit https://ibn.fm/IFnA7

About Eloro Resources Ltd.

Eloro is an exploration and mine-development company with a portfolio of gold and base-metal properties in Bolivia, Peru and Quebec. Eloro has an option to acquire a 100% interest in the highly prospective Iska Iska Property, which can be classified as a polymetallic epithermal-porphyry complex, a significant mineral deposit type in the Potosi Department in southern Bolivia. A recent NI 43-101 technical report on Iska Iska, which was completed by Micon International Limited, is available on Eloro’s website and under its filings on SEDAR. Iska Iska is a road-accessible, royalty-free property. Eloro also owns an 82% interest in the La Victoria Gold/Silver Project, located in the north-central mineral belt of Peru, some 50 kilometers south of the Lagunas Norte Gold Mine and the La Arena Gold Mine. For more information about the company, visit www.EloroResources.com .

NOTE TO INVESTORS: The latest news and updates relating to ELRRF are available in the company’s newsroom at https://ibn.fm/ELRRF

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Austin, Texas
www.MissionIR.com
512.354.7000 Office
[email protected]

MissionIR is powered by IBN

Posted in Eloro Resources Ltd. ELRRF | Leave a comment

MissionIRNewsBreaks – Soligenix Inc. (NASDAQ: SNGX) Moves Forward to Strengthen the Case for HyBryte(TM)

Soligenix (NASDAQ: SNGX), a late-stage biopharmaceutical company, is advancing its phase 3 replication study (“FLASH2”) for HyBryte(TM), a novel photodynamic therapy designed to treat early-stage cutaneous T-cell lymphoma (“CTCL”). Building on the success of a prior phase 3 trial, HyBryte(TM)—which uses synthetic hypericin activated by safe visible light—offers a potentially game-changing approach by providing a noninvasive, well-tolerated alternative that targets malignant T-cells with precision. With patient enrollment underway and interim analysis expected in early 2026, the study is designed to potentially meet the stringent requirements of regulatory agencies in order to strengthen the case for HyBryte(TM) as a commercially available treatment. This milestone emphasizes Soligenix’s broader strategy of using innovative therapeutic approaches to tackle rare and difficult-to-treat diseases. The progress of HyBryte(TM) also underscores the importance of photodynamic therapy as a new and effective modality that could potentially be applied to other dermatological and oncological conditions.

To view the full article, visit https://ibn.fm/zoXtR

About Soligenix Inc.
Soligenix is a late-stage biopharmaceutical company focused on developing and commercializing products to treat rare diseases where there is an unmet medical need. Its Specialized BioTherapeutics business segment is developing and moving toward potential commercialization of HyBryte(TM) (“SGX301” or synthetic hypericin sodium) as a novel photodynamic therapy utilizing safe visible light for the treatment of cutaneous T-cell lymphoma (“CTCL”). With successful completion of the second Phase 3 study, regulatory approvals will be sought to support potential commercialization worldwide. Development programs in this business segment also include expansion of synthetic hypericin (“SGX302”) into psoriasis, the company’s first-in-class innate defense regulator (“IDR”) technology, dusquetide (“SGX942”) for the treatment of inflammatory diseases, including oral mucositis in head and neck cancer, and (“SGX945”) in Behçet’s disease.

Soligenix’s Public Health Solutions business segment includes development programs for RiVax(R), its ricin toxin vaccine candidate, as well as its vaccine programs targeting filoviruses (such as Marburg and Ebola) and CiVax(TM), its vaccine candidate for the prevention of COVID-19 (caused by SARS-CoV-2). The development of its vaccine programs incorporates the use of the company’s proprietary heat stabilization platform technology, known as ThermoVax(R). To date, this business segment has been supported with government grant and contract funding from the National Institute of Allergy and Infectious Diseases (“NIAID”), the Defense Threat Reduction Agency (“DTRA”) and the Biomedical Advanced Research and Development Authority (“BARDA”).

For further information regarding Soligenix, visit the company’s website at www.Soligenix.com.

NOTE TO INVESTORS: The latest news and updates relating to SNGX are available in the company’s newsroom at https://ibn.fm/SNGX

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Austin, Texas
www.MissionIR.com
512.354.7000 Office
[email protected]

MissionIR is powered by IBN

Posted in Soligenix Inc. SNGX | Leave a comment

MissionIRNewsBreaks – HeartBeam Inc. (NASDAQ: BEAT) Reports Positive VALID-ECG Study Results Supporting 12-Lead ECG Technology

HeartBeam (NASDAQ: BEAT) announced that its synthesized 12-lead ECG technology met clinical endpoints in the VALID-ECG pivotal study, achieving a 93.4% diagnostic agreement with standard 12-lead ECGs for arrhythmia assessment. Results were presented by Dr. Thomas Deering of Piedmont Heart Institute during the Heart Rhythm Society’s annual conference. HeartBeam’s 3D ECG technology, designed to fit into a credit card-sized device, aims to bring hospital-grade cardiac insights to patients anywhere, with commercialization planned following anticipated FDA clearance.

To view the full press release, visit https://ibn.fm/ABvdX

About HeartBeam Inc.

HeartBeam is a medical technology company dedicated to transforming cardiac care by providing powerful cardiac insights wherever the patient is. The company is creating the first-ever cable-free 12-lead ECG capable of capturing the heart’s electrical signals from three dimensions. This platform technology is designed to be used in portable devices that can be used wherever the patient is to deliver actionable heart intelligence. Physicians will be able to identify cardiac health trends and acute conditions and direct patients to the appropriate care — all outside of a medical facility, thus redefining the future of cardiac health management. The company holds 13 U.S. and 4 international-issued patents related to technology enablement. For more information, visit www.HeartBeam.com .

NOTE TO INVESTORS: The latest news and updates relating to BEAT are available in the company’s newsroom at https://ibn.fm/BEAT

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

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www.MissionIR.com
512.354.7000 Office
[email protected]

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Posted in HeartBeam Inc. BEAT | Leave a comment

MissionIRNewsBreaks – NextPlat Corp (NASDAQ: NXPL) Receives Nasdaq Notice for Minimum Bid Price Noncompliance

NextPlat (NASDAQ: NXPL, NXPLW) announced it has received a written notice from Nasdaq Stock Market LLC stating that the company is not in compliance with Nasdaq Listing Rule 5550(a)(2), as its closing bid price has remained below $1.00 per share for 30 consecutive business days. NextPlat has been granted a 180-calendar day period, until Oct. 27, 2025, to regain compliance by maintaining a minimum $1.00 closing bid price for at least 10 consecutive business days. The company may qualify for an additional 180-day extension if it meets other listing requirements. NextPlat stated it is actively pursuing strategies to improve business efficiency and protect shareholder value while considering options to regain compliance.

To view the full press release, visit: https://ibn.fm/hGBhO

About NextPlat Corp

NextPlat is a global e-commerce platform company created to capitalize on multiple high-growth sectors and markets including technology and healthcare. Through acquisitions, joint ventures and collaborations, the company intends to assist businesses in selling their goods online, domestically, and internationally, allowing customers and partners to optimize their e-commerce presence and revenue. NextPlat currently operates an e-commerce communications division offering voice, data, tracking, and IoT products and services worldwide as well as pharmacy and healthcare data management services in the United States through its subsidiary, Progressive Care Inc.

NOTE TO INVESTORS: The latest news and updates relating to NXPL are available in the company’s newsroom at https://ibn.fm/NXPL

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Austin, Texas
www.MissionIR.com
512.354.7000 Office
[email protected]

MissionIR is powered by IBN

Posted in NextPlat Corp. NXPL | Leave a comment

Calidi Biotherapeutics Inc. (NYSE American: CLDI) Reports Innovative RTNova Platform Research, Exemplifies Pivotal Role of Research

  • “Research on the treatment of cancer is fundamental to improving outcomes for all patients affected by the disease,” reports the National Cancer Institute.
  • CLDI is reporting preclinical results for its systemic RTNova platform, which has successfully delivered transient gene therapy payloads to targeted tumors.
  • “With this breakthrough, we can use our platform to develop multiple assets for various indications,” says CEO.

Cancer remains one of the most formidable health challenges worldwide, necessitating relentless research to uncover effective treatments. Continuous scientific inquiry has led to groundbreaking therapies, offering hope to millions. A recent development in this arena is Calidi Biotherapeutics’ (NYSE American: CLDI) announcement of promising preclinical results for its systemic RTNova platform, highlighting the critical role of research in combating cancer.

The significance of research in cancer treatment cannot be overstated. Through dedicated efforts, scientists have deepened our understanding of cancer biology, leading to the development of targeted therapies that attack specific molecular abnormalities in cancer cells. This precision medicine approach has revolutionized treatment protocols, resulting in therapies that are more effective and less harmful to healthy tissues.

“Research on the treatment of cancer is fundamental to improving outcomes for all patients affected by the disease,” states the National Cancer Institute (https://ibn.fm/LO44e). “Treatment advances, in combination with innovative diagnostic tools, are leading to therapies that are increasingly tailored to the cancer’s unique traits.”

Clinical trials are integral to translating research discoveries into clinical applications. These trials rigorously evaluate the safety and efficacy of new treatments, ensuring that only those with proven benefits reach patients. Participation in clinical trials not only provides patients with access to cutting-edge therapies but also contributes to the collective understanding of cancer treatment, paving the way for future innovations.

Calidi Biotherapeutics, a clinical-stage biotechnology company, exemplifies the fruits of rigorous research in its recent announcement (https://ibn.fm/F71fk). The company is reporting promising preclinical results for its systemic RTNova platform, which has successfully delivered transient gene-therapy payloads to targeted tumors. Additionally, Calidi’s tumor-specific virotherapy demonstrated efficacy in killing more than 60 different tumor cell lines, showcasing the platform’s potential to revolutionize cancer treatment by enabling both tumor destruction and robust immune activation.

“Targeting tumors with a systemic virotherapy with a multimodal mechanism of action, which includes direct killing of the tumors and robust activation of antitumor immune responses, may revolutionize the way we approach cancer treatments,” said a Calidi spokesman. “We are excited to have shown that our systemic platform can act also as a viral vector to express therapeutic genes in target tumors, which will maximize the potential of the designed treatment. With this breakthrough, we can use our platform to develop multiple assets for various indications, opening the door for potential partnership opportunities.”

The RTNova platform addresses significant challenges in treating advanced-stage metastatic cancers, such as lung cancer, where direct tumor injection is not feasible. Calidi has engineered a novel vaccinia virus strain enveloped with a human cell membrane, known as an extracellular enveloped virus (“EEV”). This design provides protection in the bloodstream while targeting distant tumors. Upon reaching the tumor, the virotherapy selectively replicates and destroys tumor cells, inducing an immune response that trains the immune system to recognize and target future cancer cells. Furthermore, the platform’s ability to target distant tumors allows it to act as a viral vector, delivering specific gene therapies directly to tumor sites.

Research serves as the backbone of progress in cancer treatment, leading to the development of innovative therapies that improve patient outcomes. Calidi Biotherapeutics’ recent preclinical success with the RTNova platform exemplifies how dedicated research can yield promising new treatment avenues, reinforcing the vital importance of continued investment in cancer research.

Calidi Biotherapeutics is committed to advancing the RTNova platform into clinical development, aiming to provide a novel therapeutic option for patients with metastatic cancers. The company’s mission centers on leveraging cutting-edge research to develop targeted immunotherapies that address unmet medical needs in oncology. By focusing on innovative approaches like the RTNova platform, Calidi strives to transform the landscape of cancer treatment, offering new hope to patients worldwide.

For more information, visit www.CalidiBio.com.

NOTE TO INVESTORS: The latest news and updates relating to CLDI are available in the company’s newsroom at https://ibn.fm/CLDI

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Calidi Biotherapeutics Inc. CLDI | Leave a comment