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MissionIR Blog

Check out some of our latest original content that was created and distributed as part of our ongoing collaborations with IR firms and other companies.

MissionIRNewsBreaks – Why Thumzup Media Corp. (NASDAQ: TZUP) Is ‘One to Watch’

Posted on December 18, 2024 by MissionIR

Thumzup (NASDAQ: TZUP) is at the forefront of modernizing the marketing industry with its unique platform designed to connect advertisers directly with everyday social media users. “The company’s mission is to empower individuals by turning their authentic social media activity into a monetizable asset while providing brands with cost-effective and impactful advertising solutions,” reads a recent article.

“Through its flagship Thumzup platform, the company offers a seamless system where users post about participating advertisers and receive cash payments via Venmo or PayPal. Thumzup recently announced plans to integrate bitcoin as an additional payment option, expanding accessibility for gig economy workers.”

To view the full article, visit https://ibn.fm/V5eJO

About Thumzup®
Thumzup Media Corporation is democratizing the multi-billion dollar social media branding and marketing industry. Its flagship product, the Thumzup platform, utilizes a robust programmatic advertiser dashboard coupled with a consumer interface to enable individuals to get paid cash for posting about participating advertisers on major social media outlets through the Thumzup App. The easy-to-use dashboard allows advertisers to programmatically customize their campaigns. Cash payments are made to app users/creators through PayPal and other digital payment systems.

Thumzup was featured on CBS Los Angeles and in KTLA.

NOTE TO INVESTORS: The latest news and updates relating to TZUP are available in the company’s newsroom at https://ibn.fm/TZUP

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Thumzup Media Corp. TZUP | Leave a comment

SuperCom Ltd. (NASDAQ: SPCB) Enjoys Growing Influence in U.S. and European Public Safety Circles Through Superior Electronic Monitoring Technology

Posted on December 18, 2024 by MissionIR
  • Local, regional and national governments around the world are increasingly pursuing electronic monitoring (“EM”) of offenders as a means of reducing costly and often damaging incarceration
  • Latvia’s parliament recently moved a series of amendments into law that advances the country’s use of electronic monitoring (“EM”) as a tool for courts and law officers to supervise criminal suspects while allowing them to be free from incarceration
  • Israel-based SuperCom is an innovator in advanced electronic monitoring (“EM”) solutions and is building a growing list of clients in Europe and the United States
  • The company has a track record of over 50 governments and 100,000 individuals served, and has added several new contracts during the past year
  • EM monitoring is increasingly popular for preventing domestic violence (“DV”), as it helps set boundaries for DV suspects and alerts potential victims and authorities when those boundaries are at risk of being violated. Its success relies on the use of advanced technologies to ensure effectiveness

Electronic monitoring (“EM”) technology developer SuperCom (NASDAQ: SPCB) has built a worldwide reputation with its PureSecurity suite, which is used for dependable court-supervised tracking of qualifying offenders.

Bracelets, equipped with GPS and RFID capabilities, along with associated advanced technologies and solutions, have gained widespread use among court and law enforcement officials as a means of virtually detaining individuals within the community rather than behind jail bars. The bracelets can be used to ensure that probationers or suspects awaiting court decrees can be supervised while free from custody to ensure that the individuals remain confined at home or that their movements remain limited according to parameters established by law officers.

SuperCom is focused on continuing to grow its client list in North America and Europe. The company’s leadership has announced several new contracts during the past year, many of them related to domestic violence monitoring, and is particularly pleased with the $32 million project in Romania that is set to monitor about 15,000 offenders over the course of six years (https://ibn.fm/Bihmt).

SuperCom also extended its congratulations to Latvia’s parliament Saeima earlier this year as it worked to combat domestic violence through the integration of electronic monitoring services (https://ibn.fm/nE8v3), a process advanced with the final reading of proposed amendments into the Criminal Procedure Law last month, which could lead to the EM monitoring of an estimated average of 400 suspects per year, according to the amendments’ authors (https://ibn.fm/L2OZF).

“Our solutions create positive social impact and improve public safety worldwide. That is a fact,” SuperCom President and CEO Ordan Trabelsi said during a presentation of his company’s achievements last October at the LD Micro 17th Annual invitational micro-cap conference (https://ibn.fm/CJIRA). “We see this (impact) over and over in various regions,” he said. “We’re helping save the lives of potential victims. We’re aiding to eradicate domestic violence, we’re increasing public safety and well-being. … We probably have more units in domestic violence than any other player out there.”

SuperCom’s GPS technology is waterproof and has a battery life of up to one year, eliminating the need for continuous daily recharging. Its sleek design improves on the bulky ankle monitors worn in other programs, making it possible for EM supervised individuals to move about in society without being stigmatized by obvious law enforcement devices while attempting to be productive at home and work.

For more information, visit the company’s website at www.SuperCom.com.

NOTE TO INVESTORS: The latest news and updates relating to SPCB are available in the company’s newsroom at http://ibn.fm/SPCB

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in SuperCom Ltd. SPCB | Leave a comment

SuperCom Ltd. (NASDAQ: SPCB) EM Tracking Prowess is Highlighted by Growing Return on Capital Improvements

Posted on December 17, 2024 by MissionIR
  • The electronic monitoring (“EM”) industry sector has gained increased attention as a viable means to provide courts and law enforcement valuable new options for supervising offenders
  • EM’s alternative to incarceration is seen as a cost-saving measure that reduces recidivism while being responsive to community safety concerns, and this has led to financial growth in the industry
  • SuperCom, a growing EM technology developer, has reported a number of key contract wins this year in North America and Europe for its PureSecurity platform and associated services, largely based on its ability to target domestic violence prevention through EM supervision
  • A recent report by Simply Wall St noted that SuperCom has been optimizing its cash use, showing improved Return On Capital Employed (“ROCE”), and improvement in the company’s profit margin

GPS tracking technology developer SuperCom Ltd. (NASDAQ: SPCB) is gaining attention for its improving profitability amid the company’s heightened focus on court and police client electronic monitoring (“EM”). The company’s superior EM solutions allow dependable supervision of qualifying offenders while freeing them from expensive physical custody.

Simply Wall St noted in a recent article on SuperCom’s financial performance that the company’s Return On Capital Employed (“ROCE”), a metric evaluating how much pre-tax income a company earns on capital invested in its business, shows that SuperCom has already moved into positive territory for its earnings on its capital.

“Interestingly, the capital employed by the business has remained relatively flat, so these higher returns are either from prior investments paying off or increased efficiencies,” the article states, while also acknowledging that the company’s current liabilities have decreased in relation to its total assets as evidence of fundamental improvements (https://ibn.fm/SeC1g).

“Our gross profit margin improved dramatically to 50.1% from 37.7% in the prior year period,” SuperCom President and CEO Ordan Trabelsi stated in the company’s report on Q3 finances last month (https://ibn.fm/DamqX). “Looking ahead, we remain focused on executing our strategy by delivering cutting-edge solutions, deepening relationships with existing clients, and entering new markets.”

The company has put effort into optimizing its cash use for greater efficiency in employing its capital, while boosting sales in North America and Europe. SuperCom offers a unique all-in-one field-proven RFID & GPS tracking technologies product suite known as PureSecurity, tailored to the public safety sector.

The platform is enhanced by monitoring services that complement the technology and are adapted for domestic violence prevention, EM supervision of people on probation or house arrest, and other security needs.

Its technology provides improvements over legacy ankle monitor products with solutions designed to be worn discreetly with long battery life so that they don’t continually require a recharge. They also provide the potential for EM tracking on a three-dimensional plane, which is useful in metropolitan areas where residences and business offices may occupy elevated facilities within a building, and tracking movements between multiple floors is desirable rather than simply following someone on a two-dimensional map.

“Some people, especially in Manhattan, live in a certain area, so you want to make sure they’re actually in the building and in their home, not just in the building,” Trabelsi said in an interview earlier this year with the Your Advantage Play podcast (https://ibn.fm/1lWt1). “If someone’s a sex-offender and they need to stay in their house, and there is a huge building with thousands of people, it doesn’t help just to track that they’re in the building.”

SuperCom’s base of operations in Israel draws on the education and mindset inherent among the nation’s residents in defensive technologies, giving the company an added advantage in the EM security sector.

For more information, visit the company’s website at www.SuperCom.com.

NOTE TO INVESTORS: The latest news and updates relating to SPCB are available in the company’s newsroom at http://ibn.fm/SPCB

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in SuperCom Ltd. SPCB | Leave a comment

MissionIRNewsBreaks – Annovis Bio Inc. (NYSE: ANVS) Eyes Clear Path Forward for Buntanetap

Posted on December 16, 2024 by MissionIR

Annovis Bio (NYSE: ANVS) is a late-stage clinical drug platform company pioneering transformative therapies for neurodegenerative diseases, such as Alzheimer’s (“AD”) and Parkinson’s (“PD”). The company concluded the third quarter with the completion of significant milestones and a clear path forward for its lead candidate, buntanetap. “Buntanetap is an innovative drug designed to target neurodegeneration by inhibiting the formation of multiple neurotoxic proteins, including amyloid beta, tau, alpha-synuclein and TDP43,” reads a recent article. “This multifaceted inhibition improves synaptic transmission and axonal transport, reduces neuroinflammation, and protects nerve cells from dying, positioning buntanetap as a potential breakthrough in treating neurodegenerative diseases.”

To view the full article, visit https://ibn.fm/18jfD

About Annovis Bio Inc.
Headquartered in Malvern, Pennsylvania, Annovis Bio is dedicated to addressing neurodegeneration in diseases such as AD and PD. The company’s innovative approach targets multiple neurotoxic proteins, aiming to restore brain function and improve the quality of life for patients.

For more information, visit the company’s website at www.AnnovisBio.com, and social channels LinkedIn, X and YouTube.

NOTE TO INVESTORS: The latest news and updates relating to ANVS are available in the company’s newsroom at https://ibn.fm/ANVS

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Annovis Bio Inc. ANVS | Leave a comment

US Defense Department Unveils Initiatives to Expedite Adoption of AI Technologies

Posted on December 16, 2024 by MissionIR

The Chief Digital and AI office at the Pentagon has launched a rapid fielding effort to pave the way for different initiatives geared at expediting the DoD’s adoption of AI capabilities. Different units within the Pentagon will work together on an initial four AI pilot projects looking into how generative AI can be integrated into DoD enterprise management and warfighting use cases.

These four pilot projects form part of the Pentagon’s wider plan to leverage emerging technologies, so that major enablers in the Department of Defense and those who fight wars can benefit from the advantages that these technologies are capable of.

Dr. Radha Plumb, the Chief Digital & AI officer at the DoD, emphasized how important it was for the department to leverage artificial intelligence. She was speaking at the launch of the pilot projects seeking to integrate AI into the department. Plumb stated that the U.S. government and the private sector within the country had established the country as a leader in AI. However, she added adversaries like Russia, China, North Korea and Iran were also accelerating their adoption of AI, and that presented national security concerns for the U.S.

Because of those national security risks, Plumb revealed that the Defense Department was putting all hands on deck to make sure that America maintained its lead in the nascent AI field. She emphasized that the private sector had always given America the lead in innovation, and the DoD was looking to tap that resourcefulness for the benefit of national security.

The pilot projects being undertaken will help in the shaping of policy and standards while facilitating the rapid adoption of cutting-edge technologies within the department. The pilot projects will also make it possible to quickly scale AI adoption in addition to transforming how the Pentagon looks at software development and deployment.

The Artificial Intelligence Rapid Capabilities Cell (or “AI RCC”) has identified 15 use cases cutting across enterprise management and warfighting on which the four pilot projects will focus. These include cybersecurity, decision support, command and control, software development, among other use cases. The 15 use cases weren’t randomly selected; rather, a task force established last year in August identified different ways in which generative AI capabilities could be used within the DoD. The selected use cases are taken from the recommendations of that task force.

The success of these initiatives hinges on access to the necessary infrastructure and resources to support the rapid development and deployment of AI technologies. While one may immediately think of Silicon Valley companies in this context, other entities like McEwen Mining Inc. (NYSE: MUX) (TSX: MUX) play a key role in extracting minerals that are vital in the AI industry. Without these metals, the growth of the AI industry would be significantly hindered since new AI chips and data centers wouldn’t be made or constructed otherwise.

NOTE TO INVESTORS: The latest news and updates relating to MUX are available in the company’s newsroom at http://ibn.fm/MUX

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in McEwen Mining Inc. MUX | Leave a comment

MissionIRNewsBreaks – HeartBeam Inc. (NASDAQ: BEAT) Secures FDA Clearance for Innovative Arrhythmia Assessment Device

Posted on December 16, 2024 by MissionIR

HeartBeam (NASDAQ: BEAT) has received FDA 510(k) clearance for its groundbreaking HeartBeam system, a credit card-sized, cable-free ECG device designed for comprehensive arrhythmia assessment. The system enables patients to record high-fidelity heart signals from three directions during symptoms, with data transmitted to physicians for timely review and action. This milestone marks the first FDA-cleared device of its kind and lays the foundation for future advancements, including synthesized 12-lead ECGs, AI-driven arrhythmia detection, and heart attack risk assessment. HeartBeam aims to transform cardiac care by delivering actionable insights and predictive diagnostics for patients and physicians globally.

To view the full press release, visit https://ibn.fm/pDQKN

About HeartBeam Inc.

HeartBeam is a medical technology company dedicated to transforming cardiac care by providing powerful cardiac insights wherever the patient is. The company is creating the first-ever cable-free 12-lead ECG capable of capturing the heart’s electrical signals from three dimensions. This platform technology is designed to be used in portable devices that can be used wherever the patient is to deliver actionable heart intelligence. Physicians will be able to identify cardiac health trends and acute conditions and direct patients to the appropriate care — all outside of a medical facility, thus redefining the future of cardiac health management. The company holds 13 U.S. and 4 international-issued patents related to technology enablement. For more information, visit www.HeartBeam.com .

NOTE TO INVESTORS: The latest news and updates relating to BEAT are available in the company’s newsroom at https://ibn.fm/BEAT

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in HeartBeam Inc. BEAT | Leave a comment

Annovis Bio Inc. (NYSE: ANVS) Showcases 2024 Achievements and Strategic Vision in Year-End Investor Webcast

Posted on December 13, 2024 by MissionIR

Annovis Bio (NYSE: ANVS), a clinical-stage drug platform company pioneering transformative therapies for neurodegenerative diseases, recently hosted its Year-End Investor Webcast, providing stakeholders with a comprehensive overview of the company’s 2024 milestones and strategic initiatives for 2025. The full webcast is available here: https://youtu.be/NA3kCUZZIpI.

During the webcast, Dr. Maria Maccecchini, Founder, President, and CEO of Annovis Bio, detailed significant progress in the company’s pivotal Phase 3 studies for Buntanetap, its lead drug candidate targeting neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases. These studies aim to demonstrate both symptomatic relief and disease-modifying effects, aligning with Annovis Bio’s mission to address the substantial unmet needs of patients and caregivers.

“2024 has been a year of significant progress for Annovis Bio, and we are excited about the opportunities ahead,” stated Dr. Maccecchini. “Our Phase 3 programs are designed to advance our understanding of neurodegeneration and bring us closer to delivering meaningful treatments that improve patients’ lives.”

The webcast also highlighted financial developments, including the recent securing of a $50 million At-The-Market (“ATM”) offering and ongoing strategic efforts to raise additional funds to support clinical trial development and long-term growth.

Webcast Highlights Include:

  • Progress on pivotal Phase 3 Alzheimer’s and Parkinson’s clinical programs.
  • Financial updates and future fundraising plans to support key initiatives.
  • Insights into the company’s innovative approach targeting multiple neurotoxic proteins.
  • Strategic plans for 2025 to drive regulatory and clinical milestones.

The event underscores Annovis Bio’s commitment to transparency and open communication with its investors as it continues to advance its mission to combat neurodegenerative diseases through innovative therapies.

About Annovis Bio Inc.

Headquartered in Malvern, Pennsylvania, Annovis Bio Inc. is dedicated to addressing neurodegeneration in diseases such as Alzheimer’s (“AD”) and Parkinson’s (“PD”). The company’s innovative approach targets multiple neurotoxic proteins, aiming to restore brain function and improve the quality of life for patients.

For more information, visit the company’s website at www.AnnovisBio.com, and social channels LinkedIn, X and YouTube.

NOTE TO INVESTORS: The latest news and updates relating to ANVS are available in the company’s newsroom at https://ibn.fm/ANVS

About BioMedWire

BioMedWire (“BMW”) is a specialized communications platform with a focus on the latest developments in the Biotechnology (BioTech), Biomedical Sciences (BioMed), and Life Sciences sectors. It provides access to a network of wire solutions via InvestorWire to reach all target markets, industries, and demographics in the most effective manner possible. For more information, visit www.BioMedWire.com.

Forward-Looking Statements

This release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. All forward-looking statements are inherently uncertain as they are based on current expectations and assumptions concerning future events or future performance of the company. Readers are cautioned not to place undue reliance on these forward-looking statements, which are only predictions and speak only as of the date hereof. In evaluating such statements, prospective investors should review carefully various risks and uncertainties identified in this release and matters set in the company’s SEC filings. These risks and uncertainties could cause the company’s actual results to differ materially from those indicated in the forward-looking statements.

Corporate Communications

BioMedWire
Los Angeles, California
www.BioMedWire.com
310.299.1717 Office
[email protected]

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Annovis Bio Inc. ANVS | Leave a comment

Clene Inc. (NASDAQ: CLNN) Receives FDA Guidance on Accelerated Approval Pathway for CNM-Au8(R) for ALS

Posted on December 13, 2024 by MissionIR
  • The FDA asked for additional Neurofilament Light (“NfL”) data from the company’s three Expanded Access Protocols to support earlier clinical trial findings.
  • The company has already begun collecting and analyzing this data, with plans to complete the process in Q2 2025 and then submit a New Drug Application (“NDA”) for CNM-Au8 by mid-2025.
  • A follow-up meeting with the FDA will be held early next year to discuss and finalize the statistical analysis plan for the EAP NfL biomarker analyses.
  • The company is meanwhile preparing a confirmatory Phase 3 trial (“RESTORE-ALS”) to evaluate the survival benefit of CNM-Au8 with initial participant enrollment set to begin before NDA submission.

Clene (NASDAQ: CLNN) and its wholly owned subsidiary, Clene Nanomedicine Inc., a late clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis (“ALS”) and multiple sclerosis (“MS”), has received additional written guidance and a roadmap from the U.S. Food and Drug Administration’s (“FDA”) Division of Neurology 1 regarding a potential accelerated approval pathway for lead drug candidate CNM-Au8 in ALS (https://ibn.fm/8VQGo).

CNM-Au8, an oral suspension of gold nanocrystals, works by improving cellular energy production and utilization, which is critical for maintaining neuronal health. The drug candidate has already been shown to improve central nervous system cells’ survival and function via a mechanism that targets mitochondrial function and the nicotinamide adenine dinucleotide (“NAD”) pathway while reducing oxidative stress. By targeting mitochondrial dysfunction, CNM-Au8 can provide neuroprotection and promote remyelination, potentially altering the course of neurodegenerative conditions.

The FDA guidance on a potential path to meet the regulatory standard for substantial evidence of effectiveness supporting accelerated approval came following an in-person November 1 Type C meeting with the DN1 where the company presented additional clinical trial data and analyses. The FDA recommended that Clene leverage additional Neurofilament Light (“NfL”) data from its three Expanded Access Programs (“EAPs”) to support earlier findings.

Clene intends to follow the FDA’s recommendation to provide data from the ongoing EAPs and believes that it can address the FDA’s requests. The company plans to complete the additional NfL biomarker collection and analyses to support an NDA submission for CNM-Au8 during the second quarter of 2025:

  • NfL biomarker analyses: Present evidence of NfL reductions in participants enrolled in the three FDA-authorized compassionate use EAPs.
  • Survival pharmacometric modeling: Analyze NfL and related disease-specific biomarkers to evaluate their association with clinical survival benefits and observed clinical changes in Phase 2 trial data.
  • ALS-specific biomarker insights: Examine additional ALS-specific biomarkers to further support the pharmacodynamic activity of CNM-Au8 as a treatment for ALS.

Clene will have another meeting with the FDA in early 2025 to review and finalize its statistical analysis plan for the EAP NfL biomarker analyses. The FDA is expected to review whether NfL can serve as a likely surrogate endpoint for the effects of CNM-Au8 in ALS and whether the magnitude of change observed on NfL in patients treated with CNM-Au8 is likely to predict clinical benefit for ALS.

The FDA’s guidance was welcomed by Rob Etherington, President and CEO of Clene, who said the company was grateful for the regulatory body’s willingness to consider how available EAP data may support existing clinical study data to allow for the review of an accelerated regulatory pathway for CNM-Au8.

“Together with the survival and supportive biomarker data generated thus far, the drug’s benign safety profile, and the emerging EAP NfL data, we look forward to continued discussions with the Agency,” Etherington added. “Clene plans to include the additional data in an NDA submission under the accelerated approval pathway in mid-2025. We remain dedicated to the ALS community and honored to help critically ill patients and their families.”

Before filing the NDA, Clene intends to begin patient enrolment in a confirmatory Phase 3 RESTORE-ALS trial designed to investigate the effects of CNM-Au8 on improved survival (primary endpoint) and delayed time to ALS clinical worsening events (secondary efficacy endpoint).

Phase 2 clinical trial data as presented to the FDA revealed significant improvement in survival rates, functional status and combined assessment of function and survival. In addition, over 700 patient years of use of CNM-Au8 showed no significant safety concerns or safety trends. No serious adverse events have been identified as related to CNM-Au8 treatment by any investigator to date.

For more information, visit the company’s website at www.Clene.com.

NOTE TO INVESTORS: The latest news and updates relating to CLNN are available in the company’s newsroom at https://ibn.fm/CLNN

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

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www.MissionIR.com
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Posted in Clene Inc. CLNN | Leave a comment

MissionIRNewsBreaks – SolarBank Corp. (NASDAQ: SUUN) (CSE: SUNN) (NEO: SUNN) (FSE: GY2) Releases Results of Annual General and Special Meeting

Posted on December 13, 2024 by MissionIR

SolarBank (NASDAQ: SUUN) (CSE: SUNN) (NEO: SUNN) (FSE: GY2), an independent renewable and clean energy project developer and owner focusing on distributed and community solar projects in Canada and the U.S., has announced the results of its 2024 annual general and special meeting of shareholders. The nominees listed in the management information circular for the meeting were elected as directors of SolarBank. The announcement includes detailed results of the election of directors as well as other items voted for in the meeting.

To view the full press release, visit https://ibn.fm/V1JCp

About SolarBank Corporation

SolarBank Corporation is an independent renewable and clean energy project developer and owner focusing on distributed and community solar projects in Canada and the USA. The company develops solar, Battery Energy Storage System (“BESS”) and EV Charging projects that sell electricity to utilities, commercial, industrial, municipal and residential off-takers. The company maximizes returns via a diverse portfolio of projects across multiple leading North America markets including projects with utilities, host off-takers, community solar, and virtual net metering projects. The company has a potential development pipeline of over one gigawatt and has developed renewable and clean energy projects with a combined capacity of over 100 megawatts built. To learn more about SolarBank, please visit www.SolarBankCorp.com.

NOTE TO INVESTORS: The latest news and updates relating to SUUN are available in the company’s newsroom at https://ibn.fm/SUUN

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in SolarBank Corp. SUUN, Sunniva Inc. SNNVF | Leave a comment

MissionIRNewsBreaks – McEwen Mining Inc. (NYSE: MUX) (TSX: MUX) Positioned to Capitalize on the Rise of AI

Posted on December 12, 2024 by MissionIR

McEwen Mining (NYSE: MUX) (TSX: MUX) is poised to benefit amid the growing use of artificial intelligence (“AI”) in everyday life activities. As the use of AI tools trends upward, such as in the job application process among countless others, “The companies behind those AI tools could be basking in the limelight of their innovations, but behind this revolution lies several unsung heroes; including metals like gold and copper making it possible for AI components like chips and data centers to be built,” reads a recent article. “Companies such as McEwen Mining, leveraging their expertise to help address the surging demand for those minerals, are well-positioned to capitalize on the rise of AI.”

To view the full article, visit https://ibn.fm/gFpYt

About McEwen Mining Inc.
McEwen Mining is a gold and silver producer with operations in Nevada, Canada, Mexico and Argentina. In addition, it owns approximately 47.7% of McEwen Copper, which owns the large, advanced-stage Los Azules copper project in Argentina. The company’s goal is to improve the productivity and life of its assets with the objective of increasing its share price and providing a yield. Rob McEwen, MUX’s chairman and chief owner, has personally provided the company with $220 million and takes an annual salary of $1.

NOTE TO INVESTORS: The latest news and updates relating to MUX are available in the company’s newsroom at http://ibn.fm/MUX

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in McEwen Mining Inc. MUX | Leave a comment