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Check out some of our latest original content that was created and distributed as part of our ongoing collaborations with IR firms and other companies.

MissionIRNewsBreaks – Clene Inc. (NASDAQ: CLNN) Collaborates to Support Potential Accelerated Pathway for ALS Treatment Candidate

Posted on March 7, 2025 by MissionIR

Clene (NASDAQ: CLNN) and its wholly owned subsidiary, Clene Nanomedicine Inc., is partnering with APST Research GmbH to analyze neurofilament light chain (“NfL”) data in evaluating its drug candidate, CNM-Au8®, for ALS treatment. Based in Germany, APST operates one of the largest ALS biomarker repositories, which includes data from over 4,300 ALS patients. This collaboration will enable Clene to compare NfL levels in patients treated with CNM-Au8 against historical ALS controls to assess the drug’s potential in slowing disease progression. The goal is to use these findings to support FDA accelerated approval for CNM-Au8 by demonstrating its ability to reduce NfL decline and improve survival rates. Clene is planning to submit a new drug application (“NDA”) to the FDA in the second half of 2025 for potential accelerated approval. The NDA will contain data on NfL changes and survival with CNM-Au8 treatment, bolstered by results of this study. CNM-Au8, an oral suspension of gold nanocrystals, is designed to target mitochondrial dysfunction and promote neuronal health.

To view the full article, visit https://ibn.fm/8QyOh

About Clene Inc.
Clene (along with its subsidiaries, “Clene”) and its wholly owned subsidiary Clene Nanomedicine Inc., is a late clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis, Parkinson’s disease and multiple sclerosis. CNM-Au8® is an investigational first-in-class therapy that improves central nervous system cells’ survival and function via a mechanism that targets mitochondrial function and the NAD pathway while reducing oxidative stress. CNM-Au8® is a federally registered trademark of Clene Nanomedicine, Inc. The company is based in Salt Lake City, Utah, with R&D and manufacturing operations in Maryland. For more information, please visit www.Clene.com.

NOTE TO INVESTORS: The latest news and updates relating to CLNN are available in the company’s newsroom at https://ibn.fm/CLNN

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Austin, Texas
www.MissionIR.com
512.354.7000 Office
[email protected]

MissionIR is powered by IBN

Posted in Clene Inc. CLNN | Leave a comment

D-Wave Quantum Inc. (NYSE: QBTS), Staque Develop Hybrid Quantum Application to Optimize Autonomous Agriculture Vehicles

Posted on March 7, 2025 by MissionIR
  • The companies expect the application to accelerate autonomy in agriculture, streamlining agricultural operations.
  • The technology aims to enhance efficiency in large-scale farming by providing real-time optimization solutions.
  • The initiative is part of a broader strategic partnership between D-Wave and Staque to accelerate commercial adoption of annealing quantum computing.

D-Wave Quantum Inc. (NYSE: QBTS) (“D-Wave”), a leader in quantum computing systems, software, and services, and the first supplier of production-grade quantum computers, and Staque, a leading consulting and development practice in AI, blockchain and quantum computing, collaborated to develop a hybrid-quantum system designed to optimize the movements of autonomous agricultural vehicles at scale. The application, built with support from Canada’s DIGITAL Global Innovation Cluster and Verge Ag, seeks to streamline farming operations by addressing a fundamental challenge: real-time route optimization in complex environments, according to a D-Wave press release (https://ibn.fm/CmPMC).

Classical computing methods often struggle with the complexity of planning efficient movements for fleets of autonomous farming machines. Current computational methods often require days or weeks to process optimal routes, making them impractical for real-time decision-making. By leveraging D-Wave’s quantum technology, the new application aims to provide faster optimization, helping farm operators manage large-scale agricultural vehicle movements more effectively.

The application developed with Staque represents one of the first commercially viable quantum-powered solutions for the farming sector. The need for more efficient farming operations is increasing as autonomous agricultural machinery gains traction. Agricultural research institutions, equipment manufacturers, and policymakers are looking for solutions that can enhance productivity while maintaining sustainability. Quantum optimization could play a key role by helping farmers make data-driven decisions faster and more efficiently.

This initiative is part of a broader joint effort by D-Wave and Staque to accelerate the adoption of quantum computing in commercial applications. The two companies recently signed a strategic partnership, announced at the Qubits UAE event in 2024, to expand quantum-based optimization solutions.

“Traditional computation methods typically require days or weeks to compute solutions, which is too long for agricultural decision-makers,” said Krishna Ganesh, COO of Staque. “We believe in the power of quantum technology to transform and innovate, and this strategic partnership with D-Wave will allow us to provide annealing quantum computing solutions with the speed and accuracy that is important for the agriculture industry.”

“There is an urgent need to revolutionize how agriculture resources are managed and optimized,” said Dr. Muhammad Khan, project director and SVP of Innovation at Verge Ag. “Traditional computation methods are unable to provide real-time decisions that are critical to agriculture, and, as a result, we are excited about the work to build applications which could provide real-time analysis crucial for farmers and decision makers in a variety of areas including agri robotics, enhancing farming sustainability, and planning for ever-changing conditions.”

“As farmers increasingly adopt autonomous agriculture machines to scale and increase the output of their fields, we believe quantum computing can provide the analysis, speed, and accuracy necessary to maximize production and minimize costs,” said Dr. Alan Baratz, CEO of D-Wave.

About D-Wave Quantum Inc.

D-Wave is a leader in the development and delivery of quantum computing systems, software, and services. We are the world’s first commercial supplier of quantum computers, and the only company building both annealing and gate-model quantum computers. Our mission is to help customers realize the value of quantum, today. Our 5,000+ qubit AdvantageTM quantum computers, the world’s largest, are available on-premises or via the cloud, supported by 99.9% availability and uptime. More than 100 organizations trust D-Wave with their toughest computational challenges. With over 200 million problems submitted to our Advantage and Advantage2TM systems to date, our customers apply our technology to address use cases spanning optimization, artificial intelligence, research and more. Learn more about realizing the value of quantum computing today and how we’re shaping the quantum-driven industrial and societal advancements of tomorrow: www.dwavequantum.com.

NOTE TO INVESTORS: The latest news and updates relating to QBTS are available in the company’s newsroom at https://ibn.fm/QBTS

Forward Looking Statements

Certain statements in this press release are forward-looking, as defined in the Private Securities Litigation Reform Act of 1995. These statements involve risks, uncertainties, and other factors that may cause actual results to differ materially from the information expressed or implied by these forward-looking statements and may not be indicative of future results. These forward-looking statements are subject to a number of risks and uncertainties, including, among others, various factors beyond management’s control, including the risks set forth under the heading “Risk Factors” discussed under the caption “Item 1A. Risk Factors” in Part I of our most recent Annual Report on Form 10-K or any updates discussed under the caption “Item 1A. Risk Factors” in Part II of our Quarterly Reports on Form 10-Q and in our other filings with the SEC. Undue reliance should not be placed on the forward-looking statements in this press release in making an investment decision, which are based on information available to us on the date hereof. We undertake no duty to update this information unless required by law.

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in D-Wave Quantum Inc. QBTS | Leave a comment

Platinum Group Metals Ltd. (NYSE American: PLG) (TSX: PTM) Looks to Benefit from Higher Palladium Price 

Posted on March 6, 2025 by MissionIR
  • One industry expert projects that the price of palladium could double within the next decade.
  • The projected increase in palladium prices bodes well for PLG.
  • To further strengthen its strategic position, PLG has been exploring opportunities to enhance its processing capabilities.

The palladium market may be poised for a transformation over the next decade, with one industry analyst forecasting a price increase. The anticipated higher price would present a promising opportunity for companies deeply invested in palladium, such as Platinum Group Metals (NYSE American: PLG) (TSX: PTM). As an emerging player in the palladium sector, Platinum Group Metals stands to benefit from favorable market dynamics, potentially enhancing its strategic positioning.

In a recent analysis, Gaius King, a seasoned industry expert, projected that the price of palladium could double within the next 10 years (https://ibn.fm/VrkbT). King attributes this optimistic forecast to several critical factors influencing both supply and demand dynamics. He emphasizes the persistent supply constraints, noting that “palladium supply is inelastic due to the metal being a byproduct of nickel and platinum mining.” This inelasticity implies that even as demand rises, increasing the supply of palladium remains challenging, thereby exerting upward pressure on prices.

On the demand side, King highlights the robust consumption of palladium in the automotive industry, particularly in the manufacturing of catalytic converters for gasoline-powered vehicles. He points out that “stringent emission regulations worldwide are compelling automakers to use more palladium to meet environmental standards.” This regulatory landscape necessitates the incorporation of higher quantities of palladium in catalytic converters to effectively reduce harmful emissions, thereby bolstering demand.

Furthermore, King discusses the limited potential for substitution as a factor sustaining palladium’s demand. While platinum can technically replace palladium in catalytic converters, he notes that “the substitution is not straightforward due to technical challenges and the current price disparity between the two metals.” This complexity in substitution ensures that palladium will remain the preferred choice for manufacturers, maintaining its demand trajectory.

King also addresses the geopolitical risks associated with palladium production, particularly considering that a significant portion of the global supply originates from Russia. He observes that “geopolitical tensions and operational challenges in these regions can disrupt supply chains,” which could further constrain supply and contribute to price volatility. These geopolitical factors underscore the vulnerability of the palladium supply chain, potentially leading to supply shocks that drive prices higher.

An increase in palladium prices would bode well for Platinum Group Metals, which has been actively advancing its strategic initiatives to capitalize on the favorable market conditions (https://ibn.fm/iAttO). Central to PLG’s operations is the Waterberg Project, located on the Northern Limb of South Africa’s Bushveld Complex. This project is envisioned as a large-scale, fully mechanized, shallow, decline-access platinum, palladium, rhodium and gold mine. Notably, the Waterberg Project is projected to be one of the largest and lowest-cost underground platinum group metal (“PGM”) mines globally, positioning PLG advantageously in the market.

In September 2024, PLG announced positive results from an Independent Definitive Feasibility Study Update (“2024 DFS”) for the Waterberg Project (https://ibn.fm/2ANg9). The study confirmed the project’s robust economic and technical viability, reinforcing its potential to become a significant source of four important elements (“4E”) – platinum, palladium, rhodium and gold. The 2024 DFS highlighted increased mineral resources, with measured and indicated resources rising by 9.5% to 33.76 million 4E ounces, and inferred resources increasing by 6.6% to 8.52 million 4E ounces. These findings underscore the project’s capacity to meet the growing demand for palladium in coming years.

To further strengthen its strategic position, PLG has been exploring opportunities to enhance its processing capabilities. In December 2023, the company entered into a Cooperation Agreement with Ajlan & Bros. Mining and Metals Co. to study the establishment of a standalone PGM smelter and base metals refinery in Saudi Arabia. This initiative aims to provide an alternative processing route for the Waterberg Project’s output, potentially enhancing the company’s operational flexibility and market reach. The proposed facility would process PGM concentrate from the Waterberg Project, offering a strategic solution to potential bottlenecks in the existing smelting infrastructure.  Exporting PGM concentrate from South Africa to Saudi Arabia would require an approval from the government of South Africa.

In summary, the projected increase in palladium prices over the next decade presents a significant opportunity for companies such as Platinum Group Metals. With its strategic assets, proactive initiatives and robust financial planning, PLG is well-equipped to benefit from the favorable market dynamics, potentially delivering enhanced value to its stakeholders.

For more information, visit www.PlatinumGroupMetals.net.

NOTE TO INVESTORS: The latest news and updates relating to PLG are available in the company’s newsroom at https://ibn.fm/PLG

 1 345.03 million tonnes at an average grade of 3.04 4E g/t, and 0.09% Cu and 0.18% Ni.

 2 89.70 million tonnes at an average grade of 2.96 4E g/t, and 0.08% Cu, and 0.15% Ni.

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Platinum Group Metals Ltd. PLG | Leave a comment

MissionIRNewsBreaks – NextPlat Corp (NASDAQ: NXPL) to Release Full-Year 2024 Financial Results on March 17 

Posted on March 6, 2025 by MissionIR

NextPlat (NASDAQ: NXPL, NXPLW), a global e-commerce provider, announced it will release its financial results for the full-year ended Dec. 31, 2024, before market open on March 17, 2025. Executive Chairman and CEO Charles M. Fernandez, CFO Cecile Munnik, and President and CEO of Global Operations David Phipps will host a conference call at 8:30 a.m. Eastern to discuss the results and recent developments. 

To view the full press release, visit: https://ibn.fm/2aQJ7

About NextPlat Corp 

NextPlat is a global e-commerce platform company created to capitalize on multiple high-growth sectors and markets including technology and healthcare. Through acquisitions, joint ventures and collaborations, the company intends to assist businesses in selling their goods online, domestically, and internationally, allowing customers and partners to optimize their e-commerce presence and revenue. NextPlat currently operates an e-commerce communications division offering voice, data, tracking, and IoT products and services worldwide as well as pharmacy and healthcare data management services in the United States through its subsidiary, Progressive Care Inc. 

NOTE TO INVESTORS: The latest news and updates relating to NXPL are available in the company’s newsroom at  https://ibn.fm/NXPL 

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in NextPlat Corp. NXPL | Leave a comment

Newton Golf Company (NASDAQ: SPGC) Invigorates Future of Golf with Innovative Equipment, Customer Engagement

Posted on March 6, 2025 by MissionIR
  • A strategic rebranding has positioned Newton Golf as a forward-thinking entity committed to enhancing golfers’ performance through meticulously engineered products.
  • Central to Newton Golf’s product lineup are the Newton Gravity Putters and Newton Motion Shafts.
  • The company is committed to developing tools that not only enhance performance but also make the game more enjoyable.

In the ever-evolving landscape of golf equipment, Newton Golf (NASDAQ: SPGC) has emerged as a beacon of innovation and quality. Formerly operating under the name Sacks Parente Golf, the company underwent a strategic rebranding to align more closely with its mission of integrating advanced physics principles into golf-equipment design. This transformation has positioned Newton Golf as a forward-thinking entity committed to enhancing golfers’ performance through meticulously engineered products.

The rebranding initiative was officially announced late last year, marking a significant milestone in the company’s evolution (https://ibn.fm/Y1m4p). By consolidating its putter and shaft divisions under the Newton Golf umbrella, the company signaled a unified approach to product development and brand identity. This restructuring was not merely a change in name but a reflection of Newton Golf’s dedication to creating equipment that leverages the laws of physics to benefit golfers of all skill levels.

Central to Newton Golf’s product lineup are the Newton Gravity Putters and Newton Motion Shafts (https://ibn.fm/9gDMT). The gravity putters are renowned for their ultra-low balance point (“ULBP”) technology, a feature that promotes a smoother, more controlled putting stroke. This innovation has garnered attention on professional tours, with several PGA Tour champions integrating these putters into their games. The motion shafts are designed to optimize energy transfer and enhance swing consistency, embodying the company’s commitment to precision engineering.

A cornerstone of Newton Golf’s philosophy is its dedication to domestic manufacturing. All products are proudly made in the United States, with putters manufactured in Camarillo, California, and shafts handcrafted in St. Joseph, Missouri. This commitment ensures stringent quality control and supports local economies, reinforcing the company’s ethos of integrity and excellence.

The company’s vision extends beyond product innovation, encompassing a broader mission to make golf equipment that works smarter for all golfers. By focusing on the principles of physics, Newton Golf aims to develop tools that not only enhance performance but also make the game more enjoyable. This approach reflects a modern yet timeless blend of design and functionality, appealing to both traditionalists and contemporary golfers.

In addition to product development, Newton Golf places a strong emphasis on customer engagement and education. Through its website and various media outlets, the company provides insights into equipment technology, helping golfers make informed decisions about their gear. This educational approach fosters a community of informed consumers who appreciate the nuances of golf equipment and its impact on performance.

Newton Golf’s rebranding and strategic initiatives have not gone unnoticed in the golf industry. Several reputable golf publications have featured the company’s products, giving accolades for their innovative designs and performance benefits. These endorsements serve as a testament to Newton Golf’s commitment to excellence and its role as a leader in golf-equipment innovation.

Looking ahead, Newton Golf is poised to continue its trajectory of growth and innovation. With plans to expand its product offerings and further integrate advanced technologies into its designs, the company is set to solidify its position as a pioneer in the golf-equipment industry. Golfers can anticipate new developments that align with Newton Golf’s mission to make the game more accessible, enjoyable, and rewarding.

For more information, visit www.NewtonGolfCo.com.

NOTE TO INVESTORS: The latest news and updates relating to SPGC are available in the company’s newsroom at http://ibn.fm/SPGC

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in NEWTON GOLF Comp. SPGC | Leave a comment

MissionIRNewsBreaks – Clene Inc. (NASDAQ: CLNN) to Participate in 37th Annual Roth Conference

Posted on March 6, 2025 by MissionIR

Clene (NASDAQ: CLNN) a late clinical-stage biopharmaceutical company developing treatments for neurodegenerative diseases such as ALS and MS, announced its participation in the 37th Annual Roth Conference. Management will host a virtual fireside chat on March 18, 2025, at 9:20 a.m. PST and conduct one-on-one investor meetings. Interested parties are encouraged to contact their Roth representative for scheduling.

To view the full press release, visit https://ibn.fm/qjx1W

About Clene Inc.

Clene (along with its subsidiaries, “Clene”) and its wholly owned subsidiary Clene Nanomedicine Inc., is a late clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis, Parkinson’s disease and multiple sclerosis. CNM-Au8® is an investigational first-in-class therapy that improves central nervous system cells’ survival and function via a mechanism that targets mitochondrial function and the NAD pathway while reducing oxidative stress. CNM-Au8® is a federally registered trademark of Clene Nanomedicine, Inc. The company is based in Salt Lake City, Utah, with R&D and manufacturing operations in Maryland. For more information, please visit www.Clene.com.

NOTE TO INVESTORS: The latest news and updates relating to CLNN are available in the company’s newsroom at https://ibn.fm/CLNN

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Clene Inc. CLNN | Leave a comment

Calidi Biotherapeutics Inc. (NYSE American: CLDI) Pioneers Systemic Virotherapy with RTNova Platform

Posted on March 5, 2025 by MissionIR
  • Calidi’s RTNova platform leverages engineered enveloped vaccinia viruses designed for systemic delivery.
  • Calidi’s groundbreaking virotherapy holds “immense promise in revolutionizing the treatment landscape for cancer patients with advanced solid tumors,” says CEO.

Calidi Biotherapeutics (NYSE American: CLDI) is a clinical-stage biotechnology company at the forefront of developing innovative immunotherapies for cancer treatment. Most recently, the company has captured the spotlight for the development of its proprietary systemic platform, RTNova (https://ibn.fm/Z4pM3). The platform represents a significant advancement in systemic virotherapy, particularly in the utilization of enveloped virotherapies to target metastatic tumors across the body.

Antitumor virotherapy employs viruses that selectively infect and destroy cancer cells while sparing normal tissues. However, a significant challenge in the administration of these viruses is their rapid neutralization by the immune system, limiting their therapeutic efficacy.

To address this challenge, Calidi designed an innovative vaccinia virus strain enveloped with a human cell membrane (extracellular enveloped virus or EEV), providing protection in the bloodstream while targeting distant tumors (https://ibn.fm/c5fWc). Once inside the tumor, virotherapies are designed to selectively replicate and destroy tumor cells. This process activates an immune response and helps train the immune system to recognize and target future cancer cells. Additionally, the platform can target distant tumors and then act as a viral vector to deliver specific gene therapies to tumor sites.

“Calidi’s groundbreaking systemic enveloped virotherapy holds immense promise in revolutionizing the treatment landscape for cancer patients with lung cancer and metastatic advanced solid tumors,” said Allan Camaisa, Calidi Biotherapeutics CEO and board chair. “By providing protection to the virus during administration, our antitumor virotherapy is able to reach and attack the tumor sites and then activate the immune system. This is the first antitumor virotherapy with systemic administration that shows the potential for real efficacy in the clinic.”

Calidi’s innovative approach builds upon years of experience in using stem cells to protect antitumor viruses from neutralization by the patient’s immune system.

In addition to the RTNova platform, Calidi is advancing other clinical programs, including CLD-101 (NeuroNova) and CLD-201 (SuperNova), which are in various stages of development. These programs utilize stem cell–based platforms to deliver antitumor viruses, aiming to treat multiple oncology indications, such as high-grade gliomas and solid tumors. The company’s commitment to pioneering the future of cancer treatment is exemplified by its collaboration with City of Hope, where the fourth and final cohort of patients are being dosed in a phase 1 clinical trial evaluating neural stem cells carrying a tumor-killing adenovirus to treat recurrent high-grade glioma patients. Calidi also recently announced that Northwestern University commenced recruitment for a Phase 1b/2 trial using Calidi’s NeuroNova drug candidate in a multidosing strategy to treat newly diagnosed high-grade glioma.

Calidi Biotherapeutics’ dedication to harnessing the power of antitumor virotherapy positions the company as a leader in the field of cancer immunotherapy. By developing its systemic delivery mechanisms and leveraging the unique properties of enveloped viruses, Calidi is developing treatments that not only target tumors directly but also stimulate the body’s immune system to fight cancer more effectively. As its development programs progress, Calidi continues to make significant strides toward transforming the standard of care for patients with advanced and metastatic cancers.

For more information, visit www.CalidiBio.com.

NOTE TO INVESTORS: The latest news and updates relating to CLDI are available in the company’s newsroom at https://ibn.fm/CLDI

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

MissionIR
Los Angeles, CA
www.MissionIR.com
310.299.1717 Office
[email protected]

MissionIR is powered by IBN

Posted in Calidi Biotherapeutics Inc. CLDI | Leave a comment

Clene Inc. (NASDAQ: CLNN) to Highlight Latest Achievements, Next Steps for CNM-Au8(R), at Q1 Virtual Investor Summit on March 11

Posted on March 5, 2025 by MissionIR
  • The Q1 Virtual Investor Summit will focus on microcap companies that are undervalued, and aim to create connections between leading investors and microcap companies
  • Clene’s presentation will be given by CEO Rob Etherington and CFO Morgan Brown
  • Clene’s participation in the event comes as the company is moving closer to submitting a New Drug Application to the FDA to secure potential accelerated approval for CNM-Au8® for ALS
  • The company recently partnered with German-based APST Research GmbH to analyze neurofilament light chain (“NfL”) data for evaluating CNM-Au8 efficacy in ALS patients.

Clene Inc. (NASDAQ: CLNN) and its wholly owned subsidiary, Clene Nanomedicine Inc., a late clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis (“ALS”), and multiple sclerosis (“MS”), will attend the Q1 Virtual Investor Summit event on March 11 to showcase its latest achievements and outline the next steps for lead drug candidate CNM-Au8 (https://ibn.fm/YHqIv).

The company’s presentation will be given by CEO Rob Etherington and CFO Morgan Brown. The presentation starts at 1 p.m. ET. Anyone interested in participating can register at https://ibn.fm/7tHle.

The Q1 Investor Summit will consist of company presentations between 9 a.m. and 4 p.m. ET, along with one-on-one meetings between 8 a.m. and 4 p.m. An exclusive event for investors who specialize in small and microcap stocks, the Summit is a unique opportunity for investors to be introduced to and speak with management at some of the most attractive small companies, learn from various subject matter experts, and see what their peers are doing in this market. This quarter’s event focuses on microcap companies that are undervalued.

Clene’s participation in the event comes as the company is moving closer to submitting an NDA (New Drug Application) to the Food and Drug Administration (“FDA”) in the second half of 2025 to secure potential accelerated approval for CNM-Au8 for ALS.

CNM-Au8 is an oral suspension of gold nanocrystals designed to improve cellular energy production and utilization, which is critical for maintaining neuronal health. The drug candidate has been shown to improve central nervous system cells’ survival and function via a mechanism that targets mitochondrial function and the nicotinamide adenine dinucleotide pathway while reducing oxidative stress. By targeting mitochondrial dysfunction, CNM-Au8 can provide neuroprotection and promote remyelination.

The drug candidate has a robust safety profile and has provided evidence of survival benefit from two independent, randomized, double-blind, placebo-controlled clinical trials so far. In these two Phase 2 clinical trials, RESCUE-ALS and the HEALEY ALS Platform Trial, Regimen C, participants who were administered CNM-Au8 saw significant improvement in survival rates, delayed time to clinical worsening, and improvements on the combined assessment of function and survival compared to placebo. These results are supported by declines in the key plasma biomarker, NfL.

The company recently signed an agreement with APST Research GmbH (“APST”) to further analyze NfL data. The data will support analyses recommended by the FDA on the effects of CNM-Au8 in an additional cohort of ALS patients. Clene will use APST’s extensive dataset to compare NfL levels in NIH-sponsored Expanded Access Protocol (“EAP”) participants treated with CNM-Au8 against matched historical ALS controls. The goal is to determine if CNM-Au8 treatment reduces NfL decline, and to demonstrate that the rate of NfL change is associated with survival in the NIH-sponsored EAP ALS population, which would further strengthen Clene’s case for regulatory approval.

There is currently no cure available for ALS, and treatments can only help slow down the disease progression, manage the symptoms, and prevent unnecessary complications. CNM-Au8 can help increase and improve survival rates in ALS patients by enabling the body’s main systems, primarily breathing, to continue. An accelerated approval pathway for CNM-Au8 would offer hope and help obtain the best outcome for people living with ALS, the company believes. According to CDC statistics, approximately 5,000 Americans are diagnosed with ALS each year, and about 30,000 people are currently living with the disease in the U.S. alone (https://ibn.fm/A0t4F).

For more information, visit the company’s website at www.Clene.com.

NOTE TO INVESTORS: The latest news and updates relating to CLNN are available in the company’s newsroom at https://ibn.fm/CLNN

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

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MissionIRNewsBreaks – Massimo Group (NASDAQ: MAMO) Strengthens Retail Partnerships at Industry Events

Posted on March 5, 2025 by MissionIR

Massimo Group (NASDAQ: MAMO), a manufacturer of powersports vehicles, is deepening relationships with key retail partners through participation in major industry events. The company recently attended the Rural King Vendor Summit in Mattoon, Illinois, and is currently engaging with Tractor Supply Company & PetSense representatives at their ASM and Partner Trade Show in Nashville, Tennessee. These events allow Massimo to collaborate with store managers, buyers, and executives to align its UTVs, ATVs, and outdoor equipment with customer needs. The company aims to enhance its market presence by leveraging direct feedback from retail partners and expanding its strategic partnerships.

To view the full press release, visit https://ibn.fm/Bijau

About Massimo Group

Massimo Group (NASDAQ: MAMO) is a manufacturer and distributor of powersports vehicles and pontoon boats. Founded in 2009, Massimo Motor believes it offers some of the most value packed UTV’s, off-road, and on-road vehicles in the industry. The company’s product lines include a wide selection of farm and ranch tested utility UTVs, recreational ATVs, and Americana style mini-bikes. Founded in 2020, Massimo Marine manufacturers and sells Pontoon and Tritoon boats with a dedication to innovative design, quality craftsmanship, and great customer service. Massimo Group is also developing electric versions of UTVs, golf-carts and pontoon boats. The company’s 376,000 square foot factory is in the heart of the Dallas / Fort Worth area of Texas in the city of Garland . For more information, visit massimomotor.com and massimomarine.com .

NOTE TO INVESTORS: The latest news and updates relating to MAMO are available in the company’s newsroom at https:/ibn.fm/MAMO

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

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Thumzup Media Corp. (NASDAQ: TZUP) is Democratizing the $200 Billion Social Media Advertising Industry

Posted on March 4, 2025 by MissionIR
  • A hidden investor opportunity, Thumzup Media Corporation is starting to overturn the social media branding and marketing industry with an innovative approach to small business advertising
  • The company expects to grow its advertiser network 10x by the end of the year, the first step toward getting 10% of America’s small businesses to advertise on the platform and directing 20% of their ad budgets to Thumzup
  • This goal follows the 230% advertiser base growth seen in 2024, coupled with the company’s market expansion to South Florida and Greater Los Angeles

Thumzup (NASDAQ: TZUP), a Los Angeles-based company, is democratizing the $200 billion social media advertising industry with an increasingly popular platform designed to connect small-business advertisers directly with everyday social media users. The innovative approach has already attracted a growing list of customers, and the company has now listed on Nasdaq (https://ibn.fm/a9tlo).

Thumzup leverages a robust programmatic advertiser dashboard coupled with a consumer-facing App that allows individuals to get paid cash for posting about participating advertisers on major social media outlets. Given its integrations with Instagram, TikTok, and X (formerly Twitter), along with attribution tools and industry-leading analytics, Thumzup has managed to offer something unique in the market, a value proposition that its Founder and CEO, Robert Steele, believes will help the company reach its goal of a tenfold increase in advertisers over the next 12 months (https://ibn.fm/lQaZX).

In a recent letter to shareholders, Mr. Steele highlighted a 230% advertiser base growth for the 2024 calendar year. This meant that Thumzup crossed the 600 active advertisers mark and plans to grow the numbers substantially in 2025. The company also successfully listed on the Nasdaq and upsized its public offering to $8.2 million. These milestones were primarily driven by the company’s unique value proposition, product differentiation, and strong market positioning (https://ibn.fm/ZLQ7I).

Steele explained that Thumzup set out on an aggressive market expansion plan for 2024, having expanded to South Florida and Greater Los Angeles. The plan is now to scale nationwide with extended social media integrations, and its recently launched analytics tools based on customer feedback. In addition, following board approval in January 2025, the company approved a strategy to allocate up to 90% of liquid assets to Bitcoin (“BTC”). Currently, the company holds 19.106 BTC (https://ibn.fm/ZLQ7I).

Thumzup’s initial but consistent growth has made the company optimistic that it will realize and surpass its 2025 goal, with an approach that only Thumzup offers. For small-cap investors, this represents a still hidden opportunity to jump on an accelerating train that is redefining digital advertising.

“The future value proposition of Thumzup is immense. Just as hundreds of billions of dollars in value were created by democratizing ridesharing and hospitality, our platform can democratize the $200 billion social media advertising industry. To our knowledge, no one else is doing what we do,” noted Mr. Steele (https://ibn.fm/e2lny).

For company information, visit www.ThumzupMedia.com.

NOTE TO INVESTORS: The latest news and updates relating to TZUP are available in the company’s newsroom at https://ibn.fm/TZUP

About MissionIR

MissionIR (“MIR”) is a specialized communications platform with a focus on assisting IR firms with syndicated content to enhance the visibility of private and public companies within the investment community. It is one of 70+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, MIR is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, MIR brings its clients unparalleled recognition and brand awareness.

MIR is where breaking news, insightful content and actionable information converge.

For more information, please visit www.MissionIR.com

Please see full terms of use and disclaimers on the MissionIR website applicable to all content provided by MIR, wherever published or re-published: https://www.MissionIR.com/Disclaimer

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Posted in Thumzup Media Corp. TZUP | Leave a comment